OncoThAI "Laser Assisted Therapies and Immunotherapies for Oncology" is directed by Pr. Serge MORDON.
This laboratory (INSERM, University of Lille, CHU) is composed of 2 teams:
- ImmunoPDT and Immunotherapy for Cancer directed by Pr. Nadira DELHEM
- PhysicoPDT directed by Dr. Maximilien VERMANDEL
OncoThAI develops an innovative therapy, Photodynamic Therapy (PDT), essentially for cancers that have reached a therapeutic impasse.
Indeed, the use of PDT in oncology has been of growing interest for several years.
This property would be a major asset in oncology considering the revolutionary success of anti-tumor immunotherapies over the last 3 years. Based on this rationale, the activities of the ImmunoPDT team aim to develop fundamental and translational clinical projects to characterize the effects of PDT, used alone or in combination with conventional therapies, on the regulation of the immune response.
PhysicoPDT develops the technologies required for the implementation of PDT in human clinics. In addition to mathematical modelling of mechanisms (in-silico studies), the team has recognized expertise in treatment planning, simulation, light dosimetry and medical device design.
Finally, the team relies on proven expertise in the implementation of clinical protocols to evaluate PDT, in particular thanks to a very strong involvement of clinicians within OncoThAI.