Thérapie photodynamique
Thérapie photodynamique
Bloc opératoire
Thérapie photodynamique
Thérapie photodynamique
Thérapie photodynamique
Laser therapies

LASER ASSISTED THERAPIES AND IMMUNOTHERAPIES FOR ONCOLOGY

Glioblastoma

GLIOBLASTOMA

Malignant Pleural Mesothelioma

MALIGNANT PLEURAL MESOTHELIOMA

Actinic Keratosis

ACTINIC KERATOSIS & PAGET DISEASE

Peritoneal carcinomatosis

PERITONEAL CARCINOMATOSIS

Immunotherapy

IMMUNOTHERAPY

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Participation of OncoThAI at the “Paris Dermatological Days”: December 1-5, 2020

OncoThAI is virtually present at the JPD from December 1 to 5, at the session "Topical dynamic phototherapy in dermatology" with Claire Vicentini, Heny Abi-Rached and Serge Mordon

Defense of Mathilde CHAMPEAU thesis- December 9, 2020

Mathilde CHAMPEAU will defend her PhD thesis entitled "Dissolving microneedles for an optimal transdermal delivery of an active principle used in photodynamic therapy: Development and proof of [...]

Defense of Alexandre QUILBE thesis - December 7, 2020

Alexandre QUILBE will defend his thesis entitled "IN VITRO AND IN VIVO EVALUATION OF TWO NEW THERAPEUTIC STRATEGIES TARGETED IN PANCREATIC ADENOCARCINOMA: Immunotherapy targeting Immune Checkpoint [...]

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OncoThAI “Laser Assisted Therapies and Immunotherapies for Oncology” is directed by Pr. Serge MORDON

This UMR (INSERM, University of Lille, CHU) is made up of 2 teams: ImmunoPDT and Cancer Immunotherapy led by Pr. Nadira DELHEM and PhysicoPDT led by Dr. Maximilien VERMANDEL.

OncoThAI aims to offer an innovative therapy "Photodynamic Therapy (PDT)" essentially for cancers in therapeutic impasse. Indeed, the use of PDT in oncology has seen an increasing interest in recent years. There are, moreover, significant elements supporting the hypothesis of a PDT promoting the activation of the immune response. This property would be a major asset in oncology considering the revolutionary success of anti-tumor immunotherapies.

Based on this rationale, the activities of the ImmunoPDT team aim to develop fundamental and translational clinical projects in order to characterize the effects of PDT, used alone or in combination with conventional treatments, on the regulation of the immune response.

PhysicoPDT develops the technologies necessary for the implementation of PDT in human clinics. In addition to mathematical modeling of mechanisms (in-silico studies), the team has recognized expertise in treatment planning, simulation, light dosimetry and the design of medical devices. Finally, the team relies on proven competence in the implementation of clinical protocols to assess PDT, in particular, thanks to the very strong involvement of clinicians within OncoThAI.

Main research programs concern

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